• Place de la Comédie Montpellier

    A BioHealth research program selected by the French Ministry of Research and Education in the framework of the "Laboratoires d'Excellence" initiative.

    EpiGenMed wants to foster the best BioHealth basic and clinical research and to encourage interdisciplinary projects. The EpiGenMed project was selected by the French Ministry of Research and Education in the framework of the national "Investments for the Future" program in 2011. The project received 12 million euros in funding for a 10-year period, essentially devoted to science training through the recruitment of PhD students, post-doctoral fellows and Chairs of Excellence.

    EpiGenMed involves 58 of the best research groups in Montpellier, implicated in five areas of research that cover Genome and Epigenome Dynamics, Cell cycle, Cell fate and Development, Infectious diseases and Immunology, Cell signalling and Neurobiology, Biophysics and Systems biology. It is hosted by the University of Montpellier and national science institutions and benefits from an excellent industrial environment


    Biological research is booming. If physics and informatics have changed our way of life in the 20th century, undoubtedly, during the 21st century, our lifestyle and medical care will be revolutionised by life sciences. Biology turned molecular in the 20th century, medicine will become it in the 21st. An explosion of data coming from genetics, genomics and epigenetics will give a new impetus to all life sciences, leading to important diagnostic and therapeutic breakthroughs that will improve public health exponentially. The future medical check-up will take into consideration also our genome and its products and a complete molecular balance will become part of routine analyses in probably less than a generation. This will revolutionise our knowledge, research, hospitals and patients' care.

    This merge of molecular biology, physiology and medicine demands a huge collaborative effort by scientists from different fields as well as interdisciplinary research. This is the new challenge and Montpellier is now at the forefront of this new way of doing research. This is one of the best places in Europe for BioHealth Research, with excellent basic research and university hospitals. Montpellier also has a strong industrial environment with large biotech companies and dynamic start-up firms in biomedical sciences.



    EpiGenMed will nurture and increase BioHealth research in Montpellier through advanced PhD and Post-doctoral programs, as well as the awarding of Chairs of Excellence to promising junior scientists and internationally renowned senior scientists.


    The Labex EpiGenMed project, which was submitted by Giacomo Cavalli in response to the "Investments for the Future" call of the French Ministry of Research in 2011, was awarded a grant of 12 million Euros for the recruitment of PhD students, Post-doctoral fellows and Chairs of Excellence. It was the only multidisciplinary Labex project selected in the field of BioHealth Research.


    EpiGenMed gathers together 58 research groups and more than 500 scientists who cover 5 fields of research:

    • Genome and Epigenome Dynamics
    • Cell cycle, Cell fate and Development
    • Infection and Immunity
    • Integrating Systems in Neuroscience
    • Biophysics and Systems biology


    Several technical facilities for basic science, clinical and applied science as well as technology transfer services are supporting this Labex project. A BioHealth science communication program will be housed at Genopolys, a new building devoted to foster the relations between basic scientists, clinicians, industrials and lay people.


    The Labex EpiGenMed is directed by Marcel Méchali (Institute of Human Genetics, CNRS) with a Board of Directors for Scientific formation (Pierre-Emmanuel Milhiet, Center for Structural Biochemistry), Chairs of Excellence (Giacomo Cavalli, Institute of Human Genetics, CNRS), Communications and Clinical Relationship (Marc Piechaczyk, Institute of Molecular Genetics) and Translational Research (Jacques Mercier, University Hospital Center of Montpellier).


    The strategic governance relies on a Steering Board composed of the Board of Directors as well as the representatives of the institutions involved in the Labex, and on an International Advisory Committee that can provide recommendations.


    The Scientific Council includes the Board of Directors and six other members who represent the six scientific axis', the Director of the Science Doctoral School and a University representative. It is composed of: Marcel Méchali (Labex EpigenMed's Director, Board Labex), Giacomo Cavalli (Board Labex), Marc Piechaczyk (Board Labex), Pierre-Emmanuel Milhiet (Board Labex, Representative axis 5), Robert Feil (Representative axis 1), Simonetta Piatti (Representative axis 2), Monsef Benkirane (Representative axis 3), Laurent Fagni (Representative axis 4), Sofia Kossida (Director doctoral school CBS2) and Jacques Mercier (University of Montpellier's Vice-President in the field of research). The Scientific Council takes major decisions in all selection processes for the different Labex programs (PhD, Postdoc, Chair of Excellence, Labex Grants etc.).


    The EpiGenMed program illustrates and reinforces the dynamics and qualities of basic and clinical research and contributes to the international reputation of Montpellier in life sciences.


     Marcel Méchali



EpiGenMed Last Dance

Parent Category: Actualités Published: Tuesday, 11 October 2022
2022 Affiche closing conference Labex 

EpiGenMed Last Dance

Labex EpiGenMed closing conference

07-09 December 2022


After ten years of research in BioHealth involving 58 scientific teams in 14 institutes in Montpellier, the Labex EpiGenMed will close at the end of 2022 with a three-days closing conference!

Dates: December 07, 2022, 2 pm – December 09, 2022, 12 am
Venue: Faculté de Médecine Montpellier
Campus Santé Arnaud de Villeneuve
641 avenue du Doyen Gaston Giraud, 34070 Montpellier


The final program is available here.


Registration is free but compulsory!

You can find the registration form here.


Confirmed speakers:

Nathalie Arhel (IRIM, Montpellier)*

Studying nucleo-cytoplasmic trafficking to identify new broad-spectrum anitvirals.

Allison Bardin (Institut Curie, Paris)

Genome instability in stem and progenitor cells

Monsef Benkirane (IGH, Montpellier)*

The journey of retroviral DNA: from its synthesis to integration into the host genome.

Serge Braun (AFM Téléthon, France)

History, achievements, promises, and issues of gene therapy

Giacomo Cavalli (IGH, Montpellier)*

3D genome organization and Polycomb proteins in gene regulation, development and in maintaining cellular memory

Angelos Constantinou (IGH, Montpellier)*

SLX4 assembles nuclear condensates that compartmentalize the SUMO-RNF4 pathway and drive DNA repair

Anne Donaldson (University of Aberdeen, UK)

Roles of Human Rif1 Isoforms in Genome Stability

Denis Duboule (Collège de France / EPFL, Lausanne)

Pseudo-embryos and the Hox Timer

Robert Feil (IGMM, Montpellier)*

Non-coding RNAs in the control of imprinted gene expression in mammals.

Alain Fischer (Université Paris Cité, Paris)

Insight into immunity to Epstein Barr virus based on the study of inborn errors

François Fuks (Free University of Brussels)

RNA Modifications in Health and Disease.

Maryse Lebrun (LPHI, Montpellier)*

Insights into the secretion mechanisms of virulence factors in apicomplexan parasites

Laurent Le Cam (IRCM, Montpellier)*

When metabolism meets the epigenome: implication in the pathogenesis of inborn metabolic disorders.

Gaëlle Legube (CBI, Toulouse)

Chromosome and chromatin dynamics at DNA double strand breaks.

Thierry Lorca (CRBM, Montpellier)*

Deciphering the mechanisms controlling mitotic entry.

Isabelle Mansuy (Ecole Polytechnique Fédérale de Zurich, University of Zurich)

How life experiences influence health across generations: Epigenetic mechanisms in the mammalian germline.

Philippe Marin (IGF, Montpellier)*

Dynamics of the 5-HT6 receptor interactome: role in neurodevelopment and cognition.

Marcelo Nollmann (CBS, Montpellier)*

Inspecting roles of 3D chromatin organization in transcription by multiplexed imaging

Philippe Pasero (IGH, Montpellier)*

Cellular responses to transcription-replication conflicts

Simonetta Piatti (CRBM, Montpellier)*

Cell cycle control of the septin cytoskeleton for cell division.

Martine Simonelig (IGH, Montpellier)*

Stem cell metabolic reprogramming by small non-coding RNAs.

Hugues de Thé (Collège de France, Paris)

From nuclear architecture to leukemia cure: emerging roles of PML.

* Member of the Labex EpiGenMed, Montpellier

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