Axis 1: Genome and Epigenome
Leaders: Robert Feil and Bernard De Massy
Covalent modifications on the DNA and the proteins that organise the chromatin are stably maintained in specific cell lineages and tissues. These modifications together constitute the epigenome and modulate nuclear functions. This Axis explores genomic and epigenomic regulation and unravels their importance in cellular identity, development and human disease. It brings together twelve teams who investigate diverse biological functions, including chromosome compaction, DNA replication, meiotic recombination, DNA damage repair, gene expression and RNA processing.
Transcription and Epigenomics in developing T-cells
Jean-Christophe ANDRAU
IGMM - UMR 5535
1919 route de Mende, 34293 Montpellier
Phone: +33 4 34 35 96 52
Email: jean-christophe.andrau@igmm.cnrs.fr
RNA Biogenesis
Edouard BERTRAND
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 96 47
Email : edouard.bertrand@igmm.cnrs.fr
Chromatin and Cell Biology
Giacomo CAVALLI
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 70
Email: giacomo.cavalli@igh.cnrs.fr
Genetic Instability and Cancer
Angelos CONSTANTINOU
IGH - UMR 9002
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 98 14
Meiosis and Recombination
Bernard DE MASSY
IGH - UMR 9004
141, rue de la Cradonille, 34396 Montpellier
Email: bernard.de-massy@igh.cnrs.fr
Biology of Repetitive Sequences
Jérôme DEJARDIN
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 45
Email: jerome.dejardin@igh.cnrs.fr
Genomic Imprinting and Development
Robert FEIL
IGMM - UMR 5535
1919, route de Mende, 34392 Montpellier
Phone: +33 4 34 35 96 63
Email: robert.feil@igmm.cnrs.fr
Chromatin and Splicing
Reini FERNANDEZ DE LUCO
IGH - UMR 9004
141, rue de la Cardonille
Phone: +33 4 34 35 99 12
Email: reini.luco@igh.cnrs.fr
Regulation of gene expression
Dom HELMLINGER
CRBM - UMR 5237
1919, route de Mende, 34293 Montpellier
Office Phone: +33 4 34 35 95 48
Lab Phone: +33 4 34 35 95 50
Email: dhelmlinger@crbm.cnrs.fr
Genome Surveillance and Stability
Domenico MAIORANO
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 73
Email: domenico.maiorano@igh.cnrs.fr
Replication and Genome Dynamics
Marcel MECHALI
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 17
Email: marcel.mechali@igh.cnrs.fr
Epigenetic Chromatin Regulation
Kazufumi MOCHIZUKI
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 18
Email: kazufumi.mochizuki@igh.cnrs.fr