Axis 1: Genome and Epigenome
Leaders: Robert Feil and Bernard De Massy
Covalent modifications on the DNA and the proteins that organise the chromatin are stably maintained in specific cell lineages and tissues. These modifications together constitute the epigenome and modulate nuclear functions. This Axis explores genomic and epigenomic regulation and unravels their importance in cellular identity, development and human disease. It brings together twelve teams who investigate diverse biological functions, including chromosome compaction, DNA replication, meiotic recombination, DNA damage repair, gene expression and RNA processing.
Maintenance of Genome Integrity during DNA Replication
Philippe PASERO
IGH - UMR 9002
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 43
Email: philippe.pasero@igh.cnrs.fr
Chromatin and DNA replication
Marta RADMAN-LIVAJA
CRBM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 96 67
Email: marta.radman-livaja@igmm.cnrs.fr
Genetic and phenotypic plasticity of cancer
Claude SARDET and Charles THEILLET
IRCM - U 1194
208 avenue des Apothicaires, 34298 Montpellier
Phone: +33 4 67 61 25 84 (Sardet) or +33 4 67 61 37 66 (Theillet)
Mobile: +33 6 21 11 00 21 (Sardet)
Email : claude.sardet@inserm.fr
RNA Metabolism
Jamal TAZI
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: + 33 4 34 35 96 85
Mobile: + 33 6 32 72 77 25
Email: jamal.tazi@igmm.cnrs.fr
