Axis 2
Axis 2: Cell Cycle, Cell Fate and Development
Leaders: Simonetta Piatti and Martine Simonelig
The obvious connections between cell cycle and tumour progression have been largely explored during the past 30 years, providing the bases for the design of effective therapeutic strategies. It is now becoming increasingly clear that regulation of the core cell cycle machinery has a key role also in cell differentiation and metazoan development.
Besides responding to external stimuli, such as nutrition, cell cycle regulators can themselves influence metabolic processes, which makes them potential therapeutic targets also for metabolic disorders, such as obesity and diabetes.
Goal of this axis is to uncover the molecular mechanisms at the heart of cell cycle and development using a multidisciplinary and multitask approach, with the future perspective to identify new prognostic markers and potential therapeutic targets for the cure of cancer, developmental and metabolic diseases.
Cell adhesion and migration in embryonic development
François FAGOTTO
CRBM - UMR 5237
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 95 24
Email: francois.fagotto@crbm.cnrs.fr
Self-renewal and differentiation of epithelia
Philippe JAY
IGF - UMR 5203/U 661
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 92 98
Email: philippe.jay@igf.cnrs.fr
Molecular Oncogenesis
Laurent LE CAM
IRCM - U 1194
208 avenue des Apothicaires, 34298 Montpellier
Phone: +33 4 67 61 23 49
Email: laurent.lecam@inserm.fr
Transcriptional control of chordate morphogenesis
Patrick LEMAIRE
CRBM - UMR 5237
1919, route de Mende, 34293
Email: patrick.lemaire@crbm.cnrs.fr
Genome and Stem Cell Plasticity in Development and Ageing
Jean-Marc LEMAITRE
IRMB - U 1183
80 rue Augustin Fliche, 34295 Montpellier
Phone: +33 4 67 33 04 52
Email: jean-marc.lemaitre@inserm.fr
Study of mechanisms which control the mitosis entry and progress
Thierry LORCA and Anna CASTRO
CRBM - UMR 5237
1919, route de Mende, 34293 Montpellier
Phones: +33 4 34 35 95 56
+ 33 4 34 35 95 58
Emails: thierry.lorca@crbm.cnrs.fr
Miotic regulation of chromosome partitioning
Simonetta PIATTI
CRBM - UMR 5237
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 95 46
Oncogenesis and Immunotherapy
Marc PIECHACZYK
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 96 49
Email: marc.piechaczyk@igmm.cnrs.fr
Tubulin code
Krzysztof ROGOWSKI
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 45
Email: krzysztof.rogowski@igh.cnrs.fr
mRNA Regulation and Development
Martine SIMONELIG
IGH - UMR 9004
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 59
Retroviruses, Envelopes and Metabolic Markers
Marc SITBON
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: +33(0)4 34 35 96 40 or 42
Email: sitbon@igmm.cnrs.fr
Molecular Homatopoiesis
Eric SOLER
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 96 57 (-55)
Email: eric.soler@igmm.cnrs.fr