Axis 3
Axis 3: Infection and Immunity
Leaders: Monsef Benkirane and Naomi Taylor
The goal of Infection and Immunity axis is to elucidate the intimate host-pathogen interactions occurring during the pathogen life cycle and to investigate unconventional pathways/approaches that will ultimately lead to optimal immune responses against invading pathogens. We aim at:
1- Better understand the strategies used by pathogens to invade and to survive within organisms and cells; these include cell recognition, adherence of cell surfaces and intercellular bridging
2- Unravel pathogen strategies for spreading throughout the organism
3- Identify host defenses against pathogens with a particular emphasis on metabolic alterations
4-Enhance adaptive and memory immune responses to pathogens, with a specific interest in clinically relevant cytokine therapies and strategies aimed at modulating antigen presenting cells (DC)
5- Further the elucidation of host-pathogen molecular interactions to identify new vulnerabilities of the pathogen
6- Characterize the variability of pathogen diversity and resistance in order to explore the possible functional consequences on the host genome
Viral Trafficking, Restriction and Innate Signaling
Nathalie ARHEL and Sébastien NISOLE
IRIM - UMR 9004
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 94 53, +33 4 34 35 94 54
Email: nathalie.arhel@irim.cnrs.fr sebastien.nisole@irim.cnrs.fr
Biology, Genetics and Pathology in pathogenic eucaryotes
Patrick BASTIEN
MIVEGEC - UMR 5290/U 224 IRD
39 avenue Charles Flahaut, 34395 Montpellier Cedex 5
Phone: +33 4 67 33 23 50
Laboratory of Molecular Virology
Monsef BENKIRANE
IGH - UMR 9002
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 99 96
Autophagy and Infections
Martine BIARD-PIECHACZYK
IRIM - UMR 9004
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 94 55
Email : martine.biard@irim.cnrs.fr
Membrane biogenesis and interactions with the host cell in Plasmodium and Toxoplasma
Catherine BRAUN-BRETON and Maryse LEBRUN
DIMNP - UMR 5235
Place Eugène Bataillon, 34095 Montpellier
Phone: +33 4 67 14 37 42, +33 4 67 14 34 55
Email : cbb@univ-montp2.fr maryse.lebrun@univ-montp2.fr
Operational Research on AIDS and Infectious Diseases
Eric DELAPORTE
TransVIHMI - UMI 223
911, avenue Agropolis, 34394 Montpellier
Phone: +33 4 67 41 62 97
Email: eric.delaporte@ird.fr
Adenovirus: receptors, trafficking & vectorology
Eric KREMER
IGMM - UMR 5535
1919, route de Mende, 34293 Montpellier
Phone: + 33 4 34 35 96 72
Email:eric.kremer@igmm.cnrs.fr
Mycobacterial Pathogenesis and Novel Therapeutic Targets
Laurent KREMER
IRIM - UMR 9004
1919, route de Mende, 34293 Montpellier
Phone: +33 4 34 35 94 47
Email: laurent.kremer@irim.cnrs.fr
Molecular Basis of Inflammation
Nadine LAGUETTE
IGH - UMR 9002
141, rue de la Cardonille, 34396 Montpellier
Phone: +33 4 34 35 98 11
Email: nadine.laguette@igh.cnrs.fr
Genetic diversity of HIV/SIV and emerging infections
Martine PEETERS
TransVIHMI - UMI 223
911, avenue Agropolis, 34396 Montpellier
Phone: +33 4 67 41 62 97
Email: martine.peeters@ird.fr
Recherche clinique sur le VIH
Jacques REYNES
TransVIHMI - UMI 223
911 avenue Agropolis, 34394 Montpellier
Phone: +33 4 67 33 67 33
Email: j-reynes@chu-montpellier.fr
Hematopoiesis and Immunotherapy
Naomi TAYLOR
IGMM - UMR 5535
1919, route de Mende, 34293
Phone:+33 4 34 35 96 28
Email: taylor@igmm.cnrs.fr